The FTD-related proteins from these panels are associated with diverse biological pathways including inflammatory processes (GZMB), tissue remodeling (MMP1 and MMP7), cell proliferation (NPDC1), oxidative stress (APEX1), vascular functioning (VEGFA), and neuronal biosynthesis and functioning (APP and GAL) [53–57]. The gene discussed is APP; the disease is frontotemporal dementia.