Some proinflammatory markers in the serum, plasma and aqueous/vitreous humor associated with inflammation-induced retinopathy includes interleukins (IL-2/4/5/6/8/10, and interferon-γ), complement system (C2/3, and CFH), CC-motif chemokine receptor (CCR3), CC-motif chemokine ligand (CCL3, CCL5, CCL21), chemotactic protein 1 (MCP-1), macrophage inflammatory protein-1 alpha/beta (MIP-1α/β), stromal cell-derived factor 1 (SDF-1), ICAM-1, VCAM-1, TNF-α, C-reactive Protein (CRP), cyclooxygenase 2 (COX-2) [108, 128, 129]. This evidence concerns the gene CXCL12 and retinal disorder.