In addition, analysis of global DNAme patterns using high-density microarray (Illumina Infinium MethylationEPIC) in the 5-azacytidine-treated MM cell line INA-6 confirmed that the reduction in DNMT proteins levels was accompanied by decreased DNAme in regions previously exhibiting a hypermethylation profile (Fig. 1b). The gene discussed is DNMT1; the disease is Miyoshi myopathy.