DENND1B and inflammatory bowel disease: For example, the IBD-associated locus at 1q31.3 and the ulcerative colitis (UC) associated locus 22q12.3 colocalised with DENND1B and TOM1 sQTLs in 18 and 10 conditions, respectively (with a strict PP4 cutoff ≥ 0.9; splice junctions chr1:197,715,074-197,772,868 and chr22:35,333,497-35,334,328, respectively; Supplementary Data 7 and 8; Fig. 7).