KAT2A and pancreatic ductal adenocarcinoma: Recently, it was found that the histone acetyltransferase (HAT) KAT2A(also known as GCN5) can act as succinyltransferase[48], which can regulate the succinylation of histone H3 affecting gene expression leading to the deterioration of pancreatic ductal adenocarcinoma (PDAC).