MAPT and Tremor: At the later stage, with blood circulation, S. eriocheiris can infect crab nerve tissue, enhance EsGSK3β phosphorylation activity to restrain the Wnt pathway in crab nerve tissue, induce abnormal tau hyperphosphorylation, cause abnormal neurotransmitter release–associated protein phosphorylation levels, and finally disturb the crab nervous system and transmit signals while causing pereiopod tremors (Fig. 8).