This also verified the results of network pharmacology and molecular docking which found that magnoflorine, nitidine chloride, and dihydrochelerythrine have a certain affinity for SRC, STAT3, and MAPK3 and are able to exert anti-RA effects by down-regulating the expression of SRC, STAT3, and MAPK3 proteins. This evidence concerns the gene STAT3 and rheumatoid arthritis.