Similarly, increased expression of NARS2 (OR: 1.064; 95% CI: 1.015–1.115; p = 0.009) and ATP5F1A (OR: 1.061; 95% CI: 1.019–1.104; p = 0.004) was causally linked to higher AD risk, highlighting roles in mitochondrial translation, and ATP synthase function in AD pathogenesis. Here, NARS2 is linked to Alzheimer disease.