SDHC and Parkinson disease: For PD, SLC25A38, SLC25A3, and SLC25A10 were critical in mitochondrial small molecule transport and metal ion homeostasis, NDUFS1 and SDHC in oxidative phosphorylation, and TFB1M and GRSF1 in mitochondrial genetic information processing and protein translation, linked to dopaminergic neuron dysfunction.