For MS, diverse pathways, including mitochondrial metabolic processes (Score 0.836), mitochondrial signaling cascades (0.832), and mitochondrial lipid biosynthesis and catabolism (0.829), were predictive, with leading genes ATAD3A (56.0), involved in mitochondrial DNA organization; POLG (49.4), a mitochondrial DNA polymerase; and ALDH4A1 (44.8), an amino acid metabolism enzyme. The gene discussed is ALDH4A1; the disease is myeloid sarcoma.