According to univariate logistic regression analysis (Table 5), several factors were significantly associated with MASLD (p < 0.005): arterial hypertension, prediabetes, or diabetes mellitus, decreased HDL, hypertriglyceridemia, the PNPLA3 rs738409 GC/GG genotype, and the PNPLA3 rs2896019 TG/GG genotype. This evidence concerns the gene PNPLA3 and prediabetes syndrome.