Among these proteins, TNFB [odds ratio (OR): 1.06, 95% Confidence Interval (CI): 1.02–1.11, p = 8.77×10−3], TSLP (OR: 1.10, 95% CI: 1.01–1.19, p = 0.028), S100A12 (OR: 1.09, 95% CI: 1.01–1.18, p = 0.03), CD244 (OR: 1.07, 95% CI: 1.00–1.13, p = 0.036), and IL33 (OR: 1.08, 95% CI: 1.00 –1.17, p = 0.048) were identified as proteins associated with elevated AD risk. The gene discussed is S100A12; the disease is Alzheimer disease.