NFE2L2 and non-small cell lung carcinoma: Moreover, Bar-Peled et al. demonstrated that NR0B1, which is a strictly NRF2-regulated protein, supporting the anchorage-independent growth of KEAP1-mutant NSCLC cells forms a multimeric transcriptional complex important for regulating a subset of the NRF2 gene expression program in NSCLC cells [7].