The performed preclinical DSC-MRI studies indicate local T2*-weighted contrast changes in magnetic susceptibility in rat C6 glioma tissues after administration of carbon-encapsulated iron nanoparticles functionalized with a monoclonal antibody (anti-CD61) against the beta 3 subunit of the rat integrin αvβ3 receptors. Here, ITGB3 is linked to glioma.