TLR2 and neuropathy: The effect of MDA7 in paclitaxel-induced neuropathy is associated with the modulation of genes encoding glutamate transporters and N-methyl-D-aspartate receptor 2B, which are molecules important in central sensitization, and neuro-immune-related genes, such as neuronal nitric oxide synthase, chemokine CX3CL, toll-like receptor 2 (TLR2), as well as leptin.