TP53 and neoplasm: The increased expression of CDKN2A, linked to inhibition of wild-type TP53, possibly promoted by LINC01133, may be associated with early tumorigenesis; (iii) the increased expression of PIK3CA, along with the slight increase in PTEN expression, may be involved in a gene switch related to optimizing epithelial–mesenchymal transition processes; (iv) the increased expression of KRAS and LINC01133 may be related to long-term tumor maintenance (Figure 8).