Another study reported by Sanguanphun et al. (2022) revealed that decanoic acid isolated from H. leucospilota exerts an anti-Parkinson effect in C. elegans PD models by partly modulating the IIS/DAF-16 pathway, attenuating DA neurodegeneration, improving DA-dependent behaviors, and reducing oxidative stress in 6-OHDA-induced C. elegans (Figure 6) [112]. The gene discussed is SCGB1D4; the disease is Parkinson disease.