KLK3 and posterior cortical atrophy: Serum Prostate-Specific Antigen (PSA) and Digital Rectal Examination (DRE) are the most widely used PCa screenings in clinical practice, following the European Association of Urology (EAU)—European Society for Radiotherapy and Oncology (ESTRO)—International Society of Geriatric Oncology (SIOG) Guidelines [2].