APC and cancer: _ConfirmMDx® (MDxHealth, Irvine, CA, USA): this is an epigenetic assay, measuring the DNA methylation status of three genes—glutathione-S-transferase P1 (GSTP1), adenomatous polyposis coli (APC), and Ras association domain-containing protein 1 (RASSF1)—in prostate biopsy tissue without cancer [39].