INS and obesity due to melanocortin 4 receptor deficiency: Moreover, VCO exhibits antidiabetic, anti-obesity, and antiasthmatic properties by enhancing insulin secretion, and inhibiting fat accumulation, alongside potent antimicrobial activity against diverse pathogens, including bacteria, viruses, fungi, and protozoa [13,68,69,70,71,72,73,74,75,76].