Multivariate Cox regression revealed three factors independently associated with 28-day mortality: ALC at the time of candidemia diagnosis (ALC ≥ 0.2 G/L vs. ALC < 0.2 G/L: 5.3% vs. 50%; HR = 0.08; 95% CI, 0.01–0.61; p = 0.015); AFP use (yes vs. no: 26.3% vs. 52%; HR 0.31; 95% CI, 0.13–0.74, p = 0.008); and the combination of a GTX and G-CSF (GTX + G-CSF vs. G-CSF alone: 20% vs. 47.4%; HR = 0.31; 95% CI, 0.11–0.85), p = 0.024). This evidence concerns the gene AFP and Candidemia.