Whey protein supplementation in patients with metabolic syndrome was efficient in the regulation of glucose metabolism, resulting in a significant reduction in HbA1c (WMD: −0.15; 95% CI: −0.29, −0.01), insulin (WMD: −0.94; 95% CI: −1.68, −0.21), and HOMA-IR (WMD: −0.20; 95% CI: −0.36, −0.05) in comparison to control in patients with metabolic syndrome and related conditions according to a meta-analysis [76]. The gene discussed is INS; the disease is metabolic syndrome.