The common pathways mainly involved the cell cycle, focal adhesion, hepatitis B, measles infection, p53 signaling, and cancer-related pathways (chronic myeloid leukemia, colorectal cancer, endometrial cancer, glioma, melanoma, pancreatic cancer, prostate cancer, renal cell carcinoma, and viral carcinogenesis). This evidence concerns the gene TP53 and hereditary clear cell renal cell carcinoma.