SUV39H1 and lymphoma: This research reported that senescence mediated by the methylation of histone H3 lysine 9 (H3K9me), induced by the acute induction of oncogenic RAS and involving Rb signaling, was dependent on histone methyltransferase Suv39h1, and Suv39h1-deficient mice showed the aggressive formation of lymphoma, as the silencing of growth-promoting genes was impaired.