Numerous studies have reported that NDEVs contain AD‐related proteins, including Aβ, total tau, p‐tau217, p‐tau181, and miRNA, making them promising candidates for early diagnosis and disease monitoring (Aharon et al. 2020; Badhwar and Haqqani 2020; Kumar et al. 2023; Cleary et al. 2025). This evidence concerns the gene MAPT and Alzheimer disease.