Additionally, several studies indicate that USP8 confers ferroptosis resistance through β-catenin stabilization or OGT-SLC7A11 axis in HCC [47], and inhibits ferroptosis via regulating OTUB1-SLC7A11 pathway in chronic obstructive pulmonary disease (COPD) [49]. The gene discussed is SLC7A11; the disease is chronic obstructive pulmonary disease.