Multiple HDAC family members displayed distinct mRNA expression variations when comparing HCC to normal samples, with remarkable differences noticed in HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, HDAC10, and HDAC11 (Figure 1A, B). The gene discussed is HDAC2; the disease is hepatocellular carcinoma.