Regarding metastasis sites, there was a significant difference between the high and low HSP90α groups in the peritoneal metastasis-negative, liver metastasis-positive, lung metastasis-negative, and lymph node metastasis-positive groups, respectively (HR: 2.212, 95% CI: 1.244-3.936, P=0.007; HR: 2.340, 95% CI: 1.124-4.873, P=0.023; HR: 1.864, 95% CI: 1.118-3.107, P=0.017; HR: 2.215, 95% CI: 1.148-4.275, P=0.018). The gene discussed is HSP90AA1; the disease is metastatic malignant neoplasm in the lymph nodes.