Compared with mRNA expression in normal prostate tissue, SLC27A2, TWSIT1, SLC45A3, APOE and ABCC4 were upregulated, while ACOX2, GSTM4, PLA2G2C, PLP1, PTGS2, HMGCLL1, PLA2G4D and SLC5A8 were downregulated in PCa tissue (Figure s1A). This evidence concerns the gene ACOX2 and posterior cortical atrophy.