The association between hematologic neoplasms and solid tumors with AHA has been scarcely documented as a rare outcome resulting from malignancy [5].​​ In a review of 105 patients with AHA and associated solid tumors, prostate, lung, and colon cancers comprised nearly half of the malignancy-associated AHA cases [6].​​ The rarity of AHA and the paucity of research investigating the potential cross-reactivity of malignancy and FVIII have made it difficult to elucidate a causal mechanism for the development of AHA. The gene discussed is F8; the disease is colonic neoplasm.