In our case, although the patient underwent continuous hemodiafiltration, both serum inorganic phosphate and calcium levels remained persistently elevated following CHOP initiation, and no abrupt rise in serum phosphorus typical of TLS was observed (Table 1). However, it is conceivable that CHOP-induced myopericarditis created a localized inflammatory milieu conducive to calcium-phosphate precipitation, contributing to the unusually rapid development of pericardial calcification. This evidence concerns the gene DDIT3 and Tumor Lysis Syndrome.