PINK1 and periodontitis: Jiang et al.’s clinical trial revealed that the expression of PINK1, Parkin, and microtubule-associated protein light chain 3 (LC3) was significantly down-regulated in clinical specimens of gingival tissues from patients with periodontitis compared to those with healthy gingival tissues, suggesting that aberrant mitophagy is relevant to periodontitis (Jiang et al., 2023a).