Pathway enrichment analysis in the CD39-high group revealed significant enrichment of the IL-4, IL-6, and CSF3/G-CSF signaling pathways, along with pathways related to the immune response to TB, neutrophil degranulation, and toll-like receptor signaling related to Myd88 (Figure 4E) (Supplementary Table S1). The gene discussed is IL6; the disease is tuberculosis.