STAT1 and lichen planopilaris: However, exploratory reanalysis of its data (GSE11905) revealed substantial transcriptomic overlap with LPP, including upregulation of interferon-stimulated genes (e.g., MX1, OASL, STAT1), CD8 + T cell cytotoxic markers (e.g., GZMB, PRF1), and downregulation of follicular keratins and desmosomal genes.