TCF7 and asthma: Further investigations revealed that the transcription factors T-cell-specific transcription factor-1 (TCF-1) and thymocyte selection-associated high mobility group box (TOX) are crucial for maintaining the immune memory and migratory function of ml-ILC2s (11).This research provides novel insights into the pathogenesis of asthma recurrence and identifies ml-ILC2s as a promising target for potential curative therapies.