Natural compounds, such as CUR and epigallocatechin gallate, have been shown to inhibit STAT3 and its related signaling pathways, thereby hindering tumorigenesis in several types of cancer, including gastric, pancreatic, and lung cancers (Ham et al. 2022; Zhu et al. 2011; Duan et al. 2016; Mukherjee and Khuda‐Bukhsh 2015). This evidence concerns the gene STAT3 and lung cancer.