Cd promoted the migration and invasion of colorectal cancer cells.Cd up-regulated the expressions of N-cadherin, vimentin, and ZEB1, while it down-regulated expression E-cadherin.The migratory andinvasive ability of Cd-exposed colorectal cancer cells decreased as the concentration of resveratrol increased.High concentrations ofresveratrol remarkably decreased the expressions of ZEB1, vimentin, and N-cadherin & increased the expressions of E-cadherin in the Cd-exposed cells. This evidence concerns the gene ZEB1 and colorectal cancer.