As illustrated in Figures 1G, H, a significant disparity in the Chao1 index was observed between TCR and BCR in the two groups, indicating that the immune repertoire richness in patients with malignant ovarian tumors was considerably diminished in comparison to patients with benign ovarian tumors (TCR: p=0.016; BCR: p=0.003; Wilcoxon tests). This evidence concerns the gene BCR and ovarian cancer.