MUC16 and metastatic malignant neoplasm in the lymph nodes: In the EC cohort, a comprehensive analysis of potential influencing factors, including age, FIGO stage, histological grade, depth of myometrial invasion, lymphovascular space involvement, lymph node metastasis, CA125 levels, and timing of cervical smear sampling, did not identify any significant associations with the concentration of cfDNA extracted from the exfoliated cervical cell samples (Table 2).