RNF43 and neoplasm: At the primary tumor site, the RNF43-mutated group had significantly more right-sided patients than left-sided patients (left-sided: 24.47%, N=69; right-sided: 52.13%, N=147), and the RNF43 wild-type cohort data were contrary (left-sided: 54.30%, N=2034; right-sided: 22.02%, N=825).