Prognostic modeling identified six ferroptosis-related genes (SLC1A5, SLC7A11, CBS, GABARAPL1, FLT3, and MT3) and three cuproptosis-related genes (ADM, CDKN2A, and GLS) significantly associated with HCC prognosis. The gene discussed is GABARAPL1; the disease is hepatocellular carcinoma.