The proportions of T&NK (CD3E and CD3D), myeloid (ITGAM and CD11b), B cells (CD19 and CD79B), plasma cells (CD27 and CD38), fibroblasts (DCN and COL3A1), and endothelial cells (VWF and CDH5) increased significantly during GC progression (Figure 1A). This evidence concerns the gene CD38 and gastric cancer.