For example, C1q/tumor necrosis factor-related protein 12 (CTRP12) has been found to reduce heart failure after myocardial infarction by modulating the TAK1-p38 MAPK/JNK signaling pathway, suggesting its potential as a therapeutic target for post-MI heart failure (16). Here, C1QTNF12 is linked to myocardial infarction.