PLAU and breast cancer: Based on publicly available BC transcriptome data, this study identified eight prognostic genes related to Cyt c in BC: CETP, CLEC11A, CYP2A6, CYP2A7, GZMB, HGF, LDHC, and PLAU. A risk model was developed, showing that high-risk patients with BC had significantly lower survival rates compared to low-risk patients.