Studies have confirmed that CD8+ T cell infiltration is associated with a good prognosis in triple-negative breast cancer (Denkert et al., 2018; Loi et al., 2014), and high mRNA expression of GNLY and GZMB in tumors is associated with a good prognosis in colorectal cancer (Pages et al., 2005). Here, CD8A is linked to colorectal cancer.