Moreover, hyperglycemia could impede the expression of HIF‐1α, an anti‐inflammatory hypoxia‐inducible factor‐1α, thereby disrupting the NLRP3/IL‐1β signaling pathway and influencing T lymphocyte differentiation, thereby compromising the body's anti‐inflammatory response against Aspergillus [14]. This evidence concerns the gene HIF1A and Hyperglycemia.