MAPT and supranuclear palsy, progressive, 1: After adjusting for age, gender, smoking status and stroke history, total tau (179.4 pg/mL vs. 169.4 pg/mL, p < 0.001) and p-tau181 (52.81 pg/mL vs. 43.72 pg/mL, p = 0.017) levels were elevated in patients with PSP compared to HCs, consistent with previous studies (Lin et al., 2018), whereas p-tau396 levels were not significantly different (Figures 1O–Q and Table 3).