In the assay of plasma inflammatory cytokines, IL-6 (4.53 pg/mL vs. 3.38 pg/mL, p = 0.001), IL-1β (6.33 pg/mL vs. 4.34 pg/mL, p < 0.001), TNF-α(13.26 pg/mL vs. 11.28 pg/mL, p = 0.033) and IFN-γ (18.42 pg/mL vs. 15.19 pg/mL, p < 0.001) were elevated in patients with PSP compared to HCs (n = 56 vs. n = 56), whereas there was no significant difference in the levels of anti-atherosclerotic cytokine IL-10 (2.12 pg/mL vs. 2.25 pg/mL, p = 0.367) after adjusting for age, gender, smoking status and stroke history (Figures 2D–H and Table 3). This evidence concerns the gene IL1B and stroke disorder.