Moreover, the overall m6A level and its related METTL3, METTL14, and WTAP protein levels, as well as cytoplasmic MALAT1-exporting IGF2BP3 and its distribution in xenograft tumor tissues, were increased in the HBx group (Fig. 6F-G, Fig. S9C). The gene discussed is METTL3; the disease is neoplasm.