Analysis of the TCGA-LIHC cohort and the cross-linking and immunoprecipitation high-throughput sequencing (CLIP-seq) data reported previously 27 revealed that the METTL3, METTL14, and WTAP proteins potentially bind to MALAT1, which is linked to HCC pathogenesis (Fig.3F). This evidence concerns the gene MALAT1 and hepatocellular carcinoma.