To assess the regulatory effect of IGF2BP3 on MALAT1 expression, our study revealed that MALAT1 expression did not affect IGF2BP3 mRNA or protein levels in HBV/HBx-expressing HCC cells, regardless of whether MALAT1 was overexpressed or knocked down (Fig. S7E-G). This evidence concerns the gene IGF2BP3 and hepatocellular carcinoma.