In the genomic analysis of LUAD, the levels of TNFAIP6 were higher in patients with advanced stages 2-4 (75%) than in those with tumor stage 1 (66%) (Fig. 1D-E), indicating that TNFAIP6 and PLK1 were markedly expressed in advanced LUAD. The gene discussed is TNFAIP6; the disease is neoplasm.