Given that TSG6 was highly upregulated in TGF-β-induced EMT (Fig. 2) and was the most highly expressed gene in active PLK1-driven EMT of NSCLC cells (Fig. S1A), we investigated whether TSG6 plays a role in inducing EMT in LUAD cells (Fig. 4). Here, PLK1 is linked to non-small cell lung carcinoma.