Liu et al. reported that in DKD, glomeruli activate mechanosensitive transcriptional regulators, such as the transcription factor serum response factor (SRF) and coactivators myocardin-related transcription factor A and B (MRTFA/B) and yes-associated protein 1 (YAP1 or YAP) 116. The gene discussed is YAP1; the disease is diabetic kidney disease.