IGKV1D-22 and persistent truncus arteriosus: Compared with those in the control group, the S100A8 and S100A9 expression levels were highly increased in neutrophils at 1 week and in macrophages at 4 weeks after TAC (Figure 1J), indicating that neutrophils and macrophages are the main sources of S100A8/A9 in TAC-treated hearts.