We examined the expressions of ITGA6 and ITGB2 across these samples and found that ITGA6, but not ITGB2, was highly expressed in fibroblasts in OM compared to AT and PT (Figure S7A-C), supporting that tumor-derived ITGA6-high exosomes are predominantly uptaken by fibroblasts in ovarian tissues. This evidence concerns the gene ITGA6 and ocular melanoma.