To investigate whether activation of astrocytic YAP could alleviate the symptoms of C9orf72-poly-GA mice by upregulating EAAT2, we treated ALS mice with XMU-MP-1, a compound that activates the downstream effector YAP by blocking MST1/2 kinase activity 72. The gene discussed is SLC1A2; the disease is amyotrophic lateral sclerosis.